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Yttrium‐Catalyzed Addition of Benzylic CH Bonds of Alkyl Pyridines to Olefins
Author(s) -
Guan BingTao,
Wang Baoli,
Nishiura Masayoshi,
Hou Zhaomin
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201208867
Subject(s) - yttrium , cationic polymerization , alkyl , alkylation , chemistry , ethylene , pyridine , catalysis , organic chemistry , medicinal chemistry , oxide
Cationic half‐sandwich yttrium alkyl complexes catalyze the ortho ‐selective benzylic CH addition of dialkyl pyridines to various olefins, such as ethylene, 1‐hexene, styrenes, and 1,3‐conjugated dienes, to afford new alkylated and allylated pyridine derivatives (see scheme; Cp=C 5 Me 5 ). A cationic half‐sandwich yttrium picolyl species, such as [CpY(2‐CH 2 ‐6‐CH 3 C 5 H 3 N)] + , has been confirmed to be a key active species in this transformation.