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Cooperative Catalysis through Noncovalent Interactions
Author(s) -
Tang Weijun,
Johnston Steven,
Iggo Jonathan A.,
Berry Neil G.,
Phelan Marie,
Lian Luyun,
Bacsa John,
Xiao Jianliang
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201208774
Subject(s) - iridium , chemistry , computer science , non covalent interactions , catalysis , ternary operation , phosphonate , combinatorial chemistry , nanotechnology , organic chemistry , materials science , molecule , hydrogen bond , programming language
One of four : A chiral phosphoric acid enables asymmetric hydrogenation of imines with an achiral iridium catalyst by virtue of noncovalent interactions. These interactions lead to the formation of a highly organized ternary complex, and the hydride is transferred highly enantioselectively.