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Improved Dynamic Nuclear Polarization Surface‐Enhanced NMR Spectroscopy through Controlled Incorporation of Deuterated Functional Groups
Author(s) -
Zagdoun Alexandre,
Rossini Aaron J.,
Conley Matthew P.,
Grüning Wolfram R.,
Schwarzwälder Martin,
Lelli Moreno,
Franks W. Trent,
Oschkinat Hartmut,
Copéret Christophe,
Emsley Lyndon,
Lesage Anne
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201208699
Subject(s) - deuterium , passivation , radical , chemistry , polarization (electrochemistry) , nuclear magnetic resonance spectroscopy , spectroscopy , photochemistry , nuclear magnetic resonance , organic chemistry , atomic physics , physics , layer (electronics) , quantum mechanics
In a spin : The use of deuterated surface passivation agents is shown to restore dynamic nuclear polarization (DNP) surface‐enhanced NMR signals that are reduced in substrates containing methyl groups, while still protecting sensitive sites on the surface (see picture). Furthermore, apolar groups such as [D 9 ]‐trimethylsiloxy (TMS) repel radicals (yellow) away from the surface, thus diminishing detrimental paramagnetic effects induced by radical proximity.