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Metabolomics Enables the Structure Elucidation of a Diatom Sex Pheromone
Author(s) -
Gillard Jeroen,
Frenkel Johannes,
Devos Valerie,
Sabbe Koen,
Paul Carsten,
Rempt Martin,
Inzé Dirk,
Pohnert Georg,
Vuylsteke Marnik,
Vyverman Wim
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201208175
Subject(s) - diatom , pheromone , metabolite , metabolomics , sex pheromone , mating , biology , computational biology , zoology , biochemistry , ecology , bioinformatics
Finding a mate : Diatoms use chemical signals to sense the presence of and find their mating partners. When the metabolic profiles of sexually active and inactive cells were compared, a highly up‐regulated metabolite generated in the attracting mating type was identified as di‐ L ‐prolyl diketopiperazine, the first diatom pheromone.