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Stable Aqueous Dispersions of Glycopeptide‐Grafted Selectably Functionalized Magnetic Nanoparticles
Author(s) -
Borase Tushar,
Ninjbadgar Tsedev,
Kapetanakis Antonios,
Roche Sandra,
O'Connor Robert,
Kerskens Christian,
Heise Andreas,
Brougham Dermot F.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201208099
Subject(s) - glycopeptide , polymerization , nanoparticle , click chemistry , aqueous solution , computer science , nanotechnology , dispersity , backtracking , dispersion (optics) , magnetic nanoparticles , chemistry , materials science , polymer chemistry , organic chemistry , physics , programming language , polymer , biochemistry , antibiotics , optics
Sweet nanomagnets : Suspensions of glycopeptide grafted magnetic nanoparticles can be produced by N ‐carboxyanhydride ring‐opening polymerization with subsequent click glycosylation. The resulting materials have a high sugar density, optimal dispersion and T 1 ‐weighted MRI properties, and bio‐recognition ability. The approach can be used to attach any type or combination of functional groups, the density of which is not limited by particle surface area.