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Palladium‐Catalyzed Oxidative Cycloaddition through CH/NH Activation: Access to Benzazepines
Author(s) -
Wang Lei,
Huang Jiayao,
Peng Shiyong,
Liu Hui,
Jiang Xuefeng,
Wang Jian
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201208076
Subject(s) - benzazepines , cycloaddition , palladium , catalysis , chemistry , oxidative phosphorylation , combinatorial chemistry , computer science , organic chemistry , biochemistry
Rings beget rings : Benzazepines, well‐known structural design elements in medicinal chemistry, are readily prepared by a one‐pot palladium‐catalyzed oxidative cycloaddition of isatins with various alkynes.

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