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Multifunctional Gold Nanorods with Ultrahigh Stability and Tunability for In Vivo Fluorescence Imaging, SERS Detection, and Photodynamic Therapy
Author(s) -
Zhang Yuan,
Qian Jun,
Wang Dan,
Wang Yalun,
He Sailing
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201207909
Subject(s) - photodynamic therapy , nanorod , in vivo , fluorescence , nanotechnology , materials science , raman scattering , raman spectroscopy , optics , chemistry , physics , microbiology and biotechnology , organic chemistry , biology
Multimodal : Gold nanorods are coated with silica/polymer mutilayers, doped with surface‐enhance Raman scattering (SERS) and fluorescence agents as well as photosensitizers. The structural and optical properties are tunable and stable in solutions and in living bodies. A real‐time and specific in vivo SERS and fluorescence detection method using this structure is applied for tumor detection and subsequent photodynamic therapy (PDT).