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Mechanism of Diphenylprolinol Silyl Ether Catalyzed Michael Addition Revisited—but Still Controversial
Author(s) -
Moberg Christina
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201207775
Subject(s) - mechanism (biology) , conjugate , enamine , silylation , nitro , chemistry , trimethylsilyl , ether , catalysis , organic chemistry , philosophy , mathematics , epistemology , mathematical analysis , alkyl
Two views : The mechanism of the conjugate addition of linear aldehydes to nitro olefins has been investigated by two research groups. In spite of extensive experimental data, important questions remain unanswered (see scheme; TMS=trimethylsilyl, En=enamine).