Premium
On‐Demand Drug Release System for In Vivo Cancer Treatment through Self‐Assembled Magnetic Nanoparticles
Author(s) -
Lee JaeHyun,
Chen KuanJu,
Noh SeungHyun,
Garcia Mitch André,
Wang Hao,
Lin WeiYu,
Jeong Heeyeong,
Kong Brian Junoh,
Stout David B.,
Cheon Jinwoo,
Tseng HsianRong
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201207721
Subject(s) - in vivo , drug , magnetic nanoparticles , drug delivery , nanotechnology , nanoparticle , targeted drug delivery , anticancer drug , on demand , materials science , pharmacology , chemistry , medicine , computer science , microbiology and biotechnology , biology , multimedia
On‐demand drug release : Magnetothermally responsive drug‐encapsulated supramolecular nanoparticles for on‐demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.