Organocatalytic Synthesis of Highly Substituted Furfuryl Alcohols and Amines | Zendy

Clark J. Stephen | Zendy; Boyer Alistair | Zendy; Aimon Anthony | Zendy; Engel García Paloma | Zendy; Lindsay David M. | Zendy; Symington Andrew D. F. | Zendy; Danoy Yves | Zendy

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Organocatalytic Synthesis of Highly Substituted Furfuryl Alcohols and Amines

Author(s) -

Clark J. Stephen,

Boyer Alistair,

Aimon Anthony,

Engel García Paloma,

Lindsay David M.,

Symington Andrew D. F.,

Danoy Yves

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201207300

Subject(s) - tetrahydrothiophene , domino , organocatalysis , nucleophile , chemistry , computer science , process (computing) , combinatorial chemistry , organic chemistry , catalysis , enantioselective synthesis , programming language

Top cat ! Tetrahydrothiophene is an efficient organocatalyst for the synthesis of highly substituted furfuryl products from readily accessible electron‐poor enynes under neutral reaction conditions. This process is applicable to a wide range of nucleophiles and enynes and can be used in a domino organocatalysis sequence.

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