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Reconstitution of Pole‐to‐Pole Oscillations of Min Proteins in Microengineered Polydimethylsiloxane Compartments
Author(s) -
Zieske Katja,
Schwille Petra
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201207078
Subject(s) - division (mathematics) , micrometer , cell division , polydimethylsiloxane , membrane , biophysics , chemistry , cell , materials science , nanotechnology , biology , physics , biochemistry , optics , mathematics , arithmetic
Cell division in bacteria is highly regulated in time and space. The use of micrometer‐sized sample volumes and model membranes allows the pole‐to‐pole oscillations of spatial regulators for bacterial cell division to be reconstituted in a synthetic minimal system (see schematic picture left as well as the confocal images of Min proteins on lipid membranes in a polydimethylsiloxane microcompartment right).