Aromatic Ring Cleavage of 2‐Amino‐4‐ tert ‐butylphenol by a Nonheme Iron(II) Complex: Functional Model of 2‐Aminophenol Dioxygenases | Zendy

Chakraborty Biswarup | Zendy; Paine Tapan Kanti | Zendy

Premium

Aromatic Ring Cleavage of 2‐Amino‐4‐ tert ‐butylphenol by a Nonheme Iron(II) Complex: Functional Model of 2‐Aminophenol Dioxygenases

Author(s) -

Chakraborty Biswarup,

Paine Tapan Kanti

Publication year - 2013

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201206922

Subject(s) - dioxygenase , cleavage (geology) , chemistry , cleave , ring (chemistry) , stereochemistry , bond cleavage , aromatic amino acids , ligand (biochemistry) , amino acid , combinatorial chemistry , catalysis , organic chemistry , biochemistry , receptor , biology , enzyme , paleontology , fracture (geology)

Biomimetic aromatic ring cleavage: An iron(II)‐2‐aminophenolate complex (see picture, right) with a tetradentate ligand reacts with dioxygen to cleave the aromatic CC bond of 2‐amino‐4‐ tert ‐butylphenolate to form 4‐ tert ‐butyl‐2‐picolinate. This complex represents a functional model of 2‐aminophenol‐1,6‐dioxygenase (APD) and 3‐hydroxyanthranilate‐3,4‐dioxygenase (HAD).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research