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Diverse Reactivity in a Rhodium(III)‐Catalyzed Oxidative Coupling of N ‐Allyl Arenesulfonamides with Alkynes
Author(s) -
Wang Dongqi,
Wang Fen,
Song Guoyong,
Li Xingwei
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206918
Subject(s) - reactivity (psychology) , rhodium , chemistry , catalysis , medicinal chemistry , oxidative phosphorylation , combinatorial chemistry , organic chemistry , biochemistry , medicine , alternative medicine , pathology
Olefinic CH activation of N ‐allyl sulfonamides in the presence of [{RhCp*Cl 2 } 2 ] (Cp*=Me 5 C 5 ) enabled their oxidative coupling with alkynes to generate 1,2‐dihydropyridines, pyridines, and cyclopentenones (see scheme; Ts= p ‐toluenesulfonyl). The type of highly substituted product formed was controlled by the substitution of the allyl group and the reaction conditions.