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Catalytic Asymmetric Synthesis of Substituted Morpholines and Piperazines
Author(s) -
Zhai Huimin,
Borzenko Andrey,
Lau Ying Yin,
Ahn Shin Hye,
Schafer Laurel L.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206826
Subject(s) - hydroamination , enantioselective synthesis , chemistry , modular design , combinatorial chemistry , catalysis , stereochemistry , computer science , organic chemistry , programming language
Under two conditions : Hydroamination catalyzed by group 4 metals is featured in the modular and enantioselective synthesis of 3‐substituted morpholines and the diastereoselective synthesis of 2,5‐substituted piperazines.