Premium
Light‐Triggered Sequence‐Specific Cargo Release from DNA Block Copolymer–Lipid Vesicles
Author(s) -
RodríguezPulido Alberto,
Kondrachuk Alina I.,
Prusty Deepak K.,
Gao Jia,
Loi Maria A.,
Herrmann Andreas
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206783
Subject(s) - zernike polynomials , copolymer , library science , chemistry , polymer , physics , computer science , optics , organic chemistry , wavefront
Vesicle buster : Versatile functionalized nanocontainers, based on the stable incorporation of 22 mer DNA‐ b ‐PPO block copolymers (DBCs) into lipid vesicles, are presented (see picture). The study shows effective and sequence‐specific cargo release from the DBC–lipid vesicles. Hybridization of these vesicles with an oligonucleotide photosensitizer allows for singlet oxygen generation upon irradiation, which induces cargo release.