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Silicon‐Nanowire‐Based Nanocarriers with Ultrahigh Drug‐Loading Capacity for In Vitro and In Vivo Cancer Therapy
Author(s) -
Peng Fei,
Su Yuanyuan,
Wei Xinpan,
Lu Yimei,
Zhou Yanfeng,
Zhong Yiling,
Lee ShuitTong,
He Yao
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206737
Subject(s) - nanocarriers , silicon nanowires , in vivo , anticancer drug , drug delivery , drug , nanotechnology , cancer therapy , cancer , medicine , computer science , pharmacology , materials science , nanowire , microbiology and biotechnology , biology
A pratical agent for cancer therapy : Silicon nanowires (SiNWs) were employed in the design of high‐performance drug nanocarriers. The SiNWs were used as nanovectors for the delivery of an anticancer drug (DOX). SiNWs feature an ultrahigh drug‐loading capacity. In vitro and in vivo experiments show that SiNW‐based nanocarriers are highly efficacious for cancer therapy (see picture).