Direct Exchange of a Ketone Methyl or Aryl Group to Another Aryl Group through CC Bond Activation Assisted by Rhodium Chelation | Zendy

Wang Jingjing | Zendy; Chen Weiqiang | Zendy; Zuo Sujing | Zendy; Liu Lu | Zendy; Zhang Xinrui | Zendy; Wang Jianhui | Zendy

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Direct Exchange of a Ketone Methyl or Aryl Group to Another Aryl Group through CC Bond Activation Assisted by Rhodium Chelation

Author(s) -

Wang Jingjing,

Chen Weiqiang,

Zuo Sujing,

Liu Lu,

Zhang Xinrui,

Wang Jianhui

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201206693

Subject(s) - rhodium , aryl , chemistry , chelation , ketone , medicinal chemistry , group (periodic table) , functional group , stereochemistry , catalysis , organic chemistry , alkyl , polymer

Swapped : Commercially available quinolinone derivatives ( 1 or 2 , see scheme) were reacted with arylboronic acids in the presence of a Rh I complex to give aryl(quinolin‐8‐yl)methanone products 3 in medium to good yields. A mechanism that involves the in situ oxidation of Rh I to Rh III by O 2 in the presence of CuI was proposed.

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