Premium
Directed Functionalization of CH Bonds: Now also meta Selective
Author(s) -
Truong Thanh,
Daugulis Olafs
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206568
Subject(s) - surface modification , generality , chemistry , group (periodic table) , combinatorial chemistry , stereochemistry , organic chemistry , psychology , psychotherapist
Give a direction : A rationally designed, removable meta ‐directing group enables the selective, remote functionalization of aromatic substrates (see scheme). The generality of the concept was shown with alkenylation reactions of hydrocinnamic acid derivatives, the selectivities of which were similar to the ones described for benzyl derivatives.