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Narrowly Dispersed Hydrophilic Molecularly Imprinted Polymer Nanoparticles for Efficient Molecular Recognition in Real Aqueous Samples Including River Water, Milk, and Bovine Serum
Author(s) -
Ma Yue,
Pan Guoqing,
Zhang Ying,
Guo Xianzhi,
Zhang Huiqi
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206514
Subject(s) - molecularly imprinted polymer , polymer , nanoparticle , aqueous solution , precipitation polymerization , polymerization , molecular imprinting , molecular recognition , chemical engineering , precipitation , chemistry , chromatography , materials science , nanotechnology , organic chemistry , molecule , radical polymerization , selectivity , physics , meteorology , engineering , catalysis
In river water, milk, and bovine serum , molecularly imprinted polymer nanoparticles with hydrophilic polymer brushes showed excellent molecular recognition (see picture). Readily prepared by precipitation polymerization with a macromolecular chain‐transfer agent, such nanoparticles are promising alternatives to antibodies for many applications owing to their superior dispersion and binding properties in biological matrices.