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Defined Hypervalent Iodine(III) Reagents Incorporating Transferable Nitrogen Groups: Nucleophilic Amination through Electrophilic Activation
Author(s) -
Souto José A.,
Martínez Claudio,
Velilla Irene,
Muñiz Kilian
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206420
Subject(s) - hypervalent molecule , electrophile , nucleophile , chemistry , amination , iodine , reagent , imine , reactivity (psychology) , electrophilic amination , combinatorial chemistry , iodine monochloride , organic chemistry , catalysis , medicine , alternative medicine , pathology
Only I and N : Hypervalent iodine(III) reagents with two reactive IN single bonds have been isolated for the first time. Their solid‐state and solution structures provide evidence for enhanced electrophilicity at iodine and nucleophilic character of the imine. As a result, improved reactivity in amination reactions and unprecedented nitrogen‐transfer reactions under metal‐free conditions are realized.