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Medication Detection by a Combinatorial Fluorescent Molecular Sensor
Author(s) -
Rout Bhimsen,
Unger Linor,
Armony Gad,
Iron Mark A.,
Margulies David
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206374
Subject(s) - fluorescence , identification (biology) , molecular recognition , aggregation induced emission , chemistry , nanotechnology , combinatorial chemistry , computer science , molecule , materials science , organic chemistry , physics , biology , botany , quantum mechanics
Working together to uncover the truth : A molecule‐sized diagnostic system combining several recognition elements and four fluorescence‐emission channels enabled the identification of a wide range of pharmaceuticals on the basis of distinct photophysical processes. The molecular sensor (see simplified representation; ID=identification) was also used to analyze drug concentrations and combinations in urine samples in a high‐throughput manner.