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Temperature‐Switched Binding of a Ru II (dppz)/DNA Light‐Switch Complex
Author(s) -
Walker Michael G.,
Gonzalez Veronica,
Chekmeneva Elena,
Thomas Jim A
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206260
Subject(s) - intercalation (chemistry) , duplex (building) , dna , chemistry , crystallography , photochemistry , stereochemistry , inorganic chemistry , biochemistry
Cool to switch on : Although a Ru(dppz)‐based complex binds to the grooves of duplex DNA at room temperature and above, it intercalates into duplex DNA at 10 °C, thus displaying a light‐switch effect (see picture, dppz=dipyridylphenazine). Furthermore, once intercalated at low temperatures, emission does not disappear, even after the bound complex is warmed up to 35 °C for several hours.