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A Remarkable Switch from a Diamination to a Hydrohydrazination Catalyst and Observation of an Unprecedented Catalyst Resting State
Author(s) -
Schwarz Andrew D.,
Onn Chee S.,
Mountford Philip
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206249
Subject(s) - catalysis , state (computer science) , chemistry , photochemistry , organic chemistry , computer science , algorithm
A small change with a big effect : Reaction of the titanium complex 1 with terminal alkynes gave the unusual acetylide–vinylhydrazide(1−) compounds 2 (R=4‐C 6 H 4 X (X=Me, CF 3 , OMe), C 6 F 5 , SiMe 3 ) as hydrohydrazination intermediates. In contrast, a complex similar to 1 with bulkier trimethylsilyl substituents in place of the isopropyl groups is known to catalyze the 1,2‐diamination of alkynes with hydrazines.