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Back Cover: Protein‐Assisted One‐Pot Synthesis and Biofunctionalization of Spherical Gold Nanoparticles for Selective Targeting of Cancer Cells (Angew. Chem. Int. Ed. 37/2012)
Author(s) -
Colombo Miriam,
Mazzucchelli Serena,
Collico Veronica,
Avvakumova Svetlana,
Pandolfi Laura,
Corsi Fabio,
Porta Francesca,
Prosperi Davide
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201206129
Subject(s) - colloidal gold , nanoparticle , nanotechnology , monoclonal antibody , cover (algebra) , materials science , recombinant dna , cancer cell , biophysics , chemistry , cancer , antibody , biochemistry , biology , engineering , gene , immunology , mechanical engineering , genetics
The use of a recombinant variant of protein A (green) as a biotemplate for the synthesis of spherical gold nanoparticles (red) is described by F. Porta, D. Prosperi et al. in their Communication on page 9272 ff. Simultaneously, monoclonal antibodies (blue) are immobilized on the nanoparticle surface in the optimal orientation for recognition by specific cell receptors. Picture by Enzo Fezzuoglio.