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Artificial Water Channels
Author(s) -
Barboiu Mihail
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201205819
Subject(s) - steric effects , membrane , bilayer , chemistry , ion channel , biophysics , water channel , chemical physics , nanotechnology , materials science , stereochemistry , biochemistry , engineering , biology , receptor , mechanical engineering , inlet
Going through the channels : Synthetic scaffolds mimicking natural protein functions have been developed that allow water/proton or only water translocation pathways in bilayer membranes (see picture). The ion‐exclusion behaviors of the synthetic systems are based on hydrophobic or dimensional steric effects, while hydrodynamic effects appear to be less important.