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Asymmetric Ion‐Pairing Catalysis
Author(s) -
Brak Katrien,
Jacobsen Eric N.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201205449
Subject(s) - enantioselective synthesis , pairing , cationic polymerization , catalysis , chemistry , molecule , combinatorial chemistry , ion , ionic bonding , reagent , chemical physics , computational chemistry , nanotechnology , materials science , organic chemistry , physics , superconductivity , quantum mechanics
Charged intermediates and reagents are ubiquitous in organic transformations. The interaction of these ionic species with chiral neutral, anionic, or cationic small molecules has emerged as a powerful strategy for catalytic, enantioselective synthesis. This review describes developments in the burgeoning field of asymmetric ion‐pairing catalysis with an emphasis on the insights that have been gleaned into the structural and mechanistic features that contribute to high asymmetric induction.