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Peptide Cross‐Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations
Author(s) -
BaduTawiah Abraham K.,
Li Anyin,
Jjunju Fred P. M.,
Cooks R. Graham
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201205044
Subject(s) - peptide , chemistry , ion , linker , combinatorial chemistry , inorganic chemistry , nanotechnology , chemical physics , organic chemistry , materials science , biochemistry , computer science , operating system
Chemical synthesis with ambient ions : Peptide cross‐linking is achieved nearly instantaneously and quantitatively by delivering solvated peptide cations in microdroplets to a cross‐linker present on a glass surface (see picture) or vice versa. The reaction can be carried out in an open laboratory environment.