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18 F Labeling of Arenes
Author(s) -
Tredwell Matthew,
Gouverneur Véronique
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201204687
Subject(s) - chemistry , nanotechnology , positron emission tomography , pet imaging , molecular imaging , radiochemistry , combinatorial chemistry , materials science , nuclear medicine , medicine , biology , microbiology and biotechnology , in vivo
Molecular imaging has witnessed an upsurge in growth, with positron emission tomography leading the way. This trend has encouraged numerous synthetic chemists to enter the field of 18 F‐radiochemistry and provide generic solutions to address the well‐recognized challenges of late‐stage fluorination. This Minireview focuses on recent developments in the 18 F‐labeling of aromatic substrates.