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Inside Cover: Watching Water Migration around a Peptide Bond (Angew. Chem. Int. Ed. 27/2012)
Author(s) -
Tanabe Kohei,
Miyazaki Mitsuhiko,
Schmies Matthias,
Patzer Alexander,
Schütz Markus,
Sekiya Hiroshi,
Sakai Makoto,
Dopfer Otto,
Fujii Masaaki
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201204562
Subject(s) - ligand (biochemistry) , peptide , acetanilide , chemistry , molecule , hydrogen bond , peptide bond , stereochemistry , receptor , organic chemistry , biochemistry
The motion of a single water ligand around a peptide bond in acetanilide was probed in real time by time‐resolved IR spectroscopy. In their Communication on page 6604 ff. , O. Dopfer, M. Fujii et al. observe that triggered by photo‐ionization, the H 2 O ligand is released from the CO site of the peptide linkage and trapped after a migration time of 5 ps at the NH site of the same peptide bond. The migration occurs via an intermediate in which the H 2 O molecule binds neither to the CO nor the NH site.