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Inside Cover: CH Activation in S‐Alkenyl Sulfoximines: An Endo 1,5‐Hydrogen Migration (Angew. Chem. Int. Ed. 28/2012)
Author(s) -
Gao Xuefeng,
Gaddam Vikram,
Altenhofer Erich,
Tata Rama Rao,
Cai Zhengxin,
Yongpruksa Nattawut,
Garimallaprabhakaran Aswin K.,
Harmata Michael
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201204561
Subject(s) - intramolecular force , alkyl , chemistry , hydride , medicinal chemistry , int , redox , cover (algebra) , hydrogen , stereochemistry , organic chemistry , computer science , operating system , mechanical engineering , engineering
A Hydride Transfer that occurs by a 6‐ endo ‐trig process initiates an intramolecular redox reaction. In their Communication on page 7016 ff., M. Harmata et al. demonstrate that heating of N‐alkyl‐, N‐allyl‐, and N‐benzyl‐substituted S‐alkenyl sulfoximines results in the formation of NH‐S‐alkyl sulfoximines under appropriate conditions. The intermediates in the reaction can also give access to four‐ and six‐membered heterocyclic rings and a new class of chiral dienes.