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Planar‐Chiral [7]Orthocyclophanes
Author(s) -
Tomooka Katsuhiko,
Iso Chisato,
Uehara Kazuhiro,
Suzuki Masaki,
NishikawaShimono Rie,
Igawa Kazunobu
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201204484
Subject(s) - intramolecular force , chirality (physics) , stereospecificity , planar chirality , planar , molecule , chemistry , stereochemistry , enantioselective synthesis , catalysis , chiral symmetry , organic chemistry , physics , computer science , computer graphics (images) , nambu–jona lasinio model , quark , quantum mechanics
Just plain chiral : The [7]orthocyclophanes 1 , having an E ‐olefinic ansa chain, exhibit planar chirality at ambient temperature and their stereochemical stabilities are highly dependent upon the embedded X group in the ansa chain. Inter‐ and intramolecular transformations of 1 (where X=NTs) provide a variety of nitrogen‐containing chiral molecules in a stereospecific manner. Ts=4‐toluenesulfonyl.