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Reductive Cleavage of the C sp 2 C sp 3 Bond of Secondary Benzyl Alcohols: Rhodium Catalysis Directed by N‐Containing Groups
Author(s) -
Chen Kang,
Li Hu,
Lei ZhiQuan,
Li Yang,
Ye WenHe,
Zhang LiSheng,
Sun Jian,
Shi ZhangJie
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201204338
Subject(s) - rhodium , cationic polymerization , catalysis , hydride , bond cleavage , chemistry , cleavage (geology) , reductive elimination , medicinal chemistry , combinatorial chemistry , organic chemistry , materials science , composite material , fracture (geology) , hydrogen
Cutting loose : 1,1‐Biarylmethanol substrates undergo reductive cleavage of the CC bond in the presence of a cationic Rh III catalyst and H 2 (see scheme; DG=directing group). Various functional groups are tolerated in the reaction system. Preliminary studies indicate that a five‐membered rhodacycle intermediate, which then converts into a Rh III hydride species for the reduction, is involved in the catalytic cycle.