Premium
Surface Topology Engineering of Membranes for the Mechanical Investigation of the Tubulin Homologue FtsZ
Author(s) -
Arumugam Senthil,
Chwastek Grzegorz,
FischerFriedrich Elisabeth,
Ehrig Carina,
Mönch Ingolf,
Schwille Petra
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201204332
Subject(s) - ftsz , cytoskeleton , tubulin , membrane , protein filament , curvature , component (thermodynamics) , biophysics , actin , cell division , microbiology and biotechnology , materials science , topology (electrical circuits) , microtubule , nanotechnology , chemistry , biology , physics , cell , engineering , geometry , biochemistry , composite material , mathematics , electrical engineering , thermodynamics
Bending over backward : Despite their small size, bacteria display highly organized cytoskeletal structures. Using microfabricated supports for model membranes, mechanical features of FtsZ (blue hexagons) filaments, a key component of bacterial cell division, can be addressed. Studying the curvature of an FtsZ filament into a groove or around a capillary (see picture) helps to understand its mechanics.