Surface Topology Engineering of Membranes for the Mechanical Investigation of the Tubulin Homologue FtsZ | Zendy

Arumugam Senthil | Zendy; Chwastek Grzegorz | Zendy; FischerFriedrich Elisabeth | Zendy; Ehrig Carina | Zendy; Mönch Ingolf | Zendy; Schwille Petra | Zendy

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Surface Topology Engineering of Membranes for the Mechanical Investigation of the Tubulin Homologue FtsZ

Author(s) -

Arumugam Senthil,

Chwastek Grzegorz,

FischerFriedrich Elisabeth,

Ehrig Carina,

Mönch Ingolf,

Schwille Petra

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201204332

Subject(s) - ftsz , cytoskeleton , tubulin , membrane , protein filament , curvature , component (thermodynamics) , biophysics , actin , cell division , microbiology and biotechnology , materials science , topology (electrical circuits) , microtubule , nanotechnology , chemistry , biology , physics , cell , engineering , geometry , biochemistry , composite material , mathematics , electrical engineering , thermodynamics

Bending over backward : Despite their small size, bacteria display highly organized cytoskeletal structures. Using microfabricated supports for model membranes, mechanical features of FtsZ (blue hexagons) filaments, a key component of bacterial cell division, can be addressed. Studying the curvature of an FtsZ filament into a groove or around a capillary (see picture) helps to understand its mechanics.

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