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Baeyer–Villiger Oxidation and Oxidative Cascade Reactions with Aqueous Hydrogen Peroxide Catalyzed by Lipophilic Li[B(C 6 F 5 ) 4 ] and Ca[B(C 6 F 5 ) 4 ] 2
Author(s) -
Uyanik Muhammet,
Nakashima Daisuke,
Ishihara Kazuaki
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201204286
Subject(s) - hydrogen peroxide , catalysis , chemistry , aqueous solution , silylation , baeyer–villiger oxidation , oxidative phosphorylation , peroxide , cascade , redox , medicinal chemistry , organic chemistry , biochemistry , chromatography
Efficient and selective : Two lipophilic catalysts were used for Baeyer–Villiger (BV) oxidations to give lactones in high yields (see scheme). Cascade reactions involving this BV oxidation were used to selectively obtain either unsaturated carboxylic acids or hydroxylactones in high yields from β‐silyl cyclohexanones.