Gold Vinylidene Complexes: Intermolecular C(sp 3 )H Insertions and Cyclopropanations Pathways | Zendy

Hashmi A. Stephen K. | Zendy; Wieteck Marcel | Zendy; Braun Ingo | Zendy; Rudolph Matthias | Zendy; Rominger Frank | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Gold Vinylidene Complexes: Intermolecular C(sp 3 )H Insertions and Cyclopropanations Pathways

Author(s) -

Hashmi A. Stephen K.,

Wieteck Marcel,

Braun Ingo,

Rudolph Matthias,

Rominger Frank

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201204015

Subject(s) - cyclopropanation , intermolecular force , synthon , cyclobutene , ring (chemistry) , chemistry , stereochemistry , cascade , medicinal chemistry , organic chemistry , molecule , catalysis , chromatography

Highly reactive gold vinylidene species are used for intermolecular C(sp 3 )H insertions into unactivated alkanes (see scheme). In addition, they can be regarded as synthons for alkylidene carbenes. Initiated by cyclopropanation of the vinylidene species/alkylidene carbenoide, cyclobutene derivatives are formed in a diastereoselective fashion by a ring‐enlargement cascade in only one step.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research