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Gold–Gold Cooperation in the Addition of Methanol to Alkynes
Author(s) -
Roithová Jana,
Janková Štěpánka,
Jašíková Lucie,
Váňa Jiří,
Hybelbauerová Simona
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201204003
Subject(s) - alkyne , methanol , chemistry , dissociation (chemistry) , photochemistry , spectroscopy , nuclear magnetic resonance spectroscopy , kinetics , reaction mechanism , combinatorial chemistry , computational chemistry , catalysis , stereochemistry , organic chemistry , physics , quantum mechanics
The gold(I)‐mediated reaction between an internal alkyne and methanol proceeds by a dual activation mechanism, which directly results in formation of gem‐ diaurated intermediates. Reaction intermediates were investigated by IR multiphoton dissociation spectroscopy, kinetics by NMR spectroscopy, and the mechanism by DFT calculations.