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Enhanced Stability in Rigid Peptide‐Based Porous Materials
Author(s) -
MartíGastaldo Carlos,
Warren John E.,
Stylianou Kyriakos C.,
Flack Natasha L. O.,
Rosseinsky Matthew J.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201203929
Subject(s) - dipeptide , rigidity (electromagnetism) , flexibility (engineering) , peptide , chemistry , computer science , porosity , combinatorial chemistry , stereochemistry , materials science , mathematics , biochemistry , organic chemistry , composite material , statistics
Pepped up : Notwithstanding the intrinsic conformational flexibility of peptides, [Zn(Gly–Thr) 2 ] behaves as a robust porous metal–organic framework thanks to the rigidity introduced by the use of Gly–Thr (see scheme). This rigidity arises from the sequence of amino acids in the dipeptide that locks its conformational flexibility in the framework.