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Gallium Tribromide Catalyzed Coupling Reaction of Alkenyl Ethers with Ketene Silyl Acetals
Author(s) -
Nishimoto Yoshihiro,
Ueda Hiroki,
Yasuda Makoto,
Baba Akio
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201203778
Subject(s) - ketene , silylation , chemistry , catalysis , acetal , organic chemistry , medicinal chemistry
A ‘Ga'llant couple : The α‐alkenylation of esters was accomplished by GaBr 3 ‐catalyzed coupling between alkenyl ethers and ketene silyl acetals. In this reaction system, various alkenyl ethers, including those with vinyl and substituted alkenyl groups, were applicable, and the scope of applicable ketene silyl acetals was sufficiently broad. The mechanism is also discussed.