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C sp 3 H Bond Activation Triggered by Formation of Metallacycles: Rhodium(I)‐Catalyzed Cyclopropanation/Cyclization of Allenynes
Author(s) -
Oonishi Yoshihiro,
Kitano Yoshitaka,
Sato Yoshihiro
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201203772
Subject(s) - chemistry , cyclopropanation , substituent , allene , catalysis , cyclopropane , moiety , ruthenium , rhodium , stereochemistry , organic synthesis , ring (chemistry) , medicinal chemistry , combinatorial chemistry , photochemistry , organic chemistry
Giving direction : An C sp 3H bond activation directed by a rhodacycle intermediate has been found to occur in a Rh I ‐catalyzed reaction between an allene moiety having a tert ‐butyl substituent, and tethered alkynes. Cyclic compounds containing a cyclopropane ring were obtained in good to high yields (up to 92%).