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Mechanistic Insights into a Supramolecular Self‐Assembling Catalyst System: Evidence for Hydrogen Bonding during Rhodium‐Catalyzed Hydroformylation
Author(s) -
Gellrich Urs,
Seiche Wolfgang,
Keller Manfred,
Breit Bernhard
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201203768
Subject(s) - hydroformylation , rhodium , catalysis , supramolecular chemistry , intermolecular force , hydrogen bond , chemistry , combinatorial chemistry , ligand (biochemistry) , catalytic cycle , organic chemistry , molecule , biochemistry , receptor
The structural integrity and flexibility provided by intermolecular hydrogen bonds leads to the outstanding properties of the 6‐diphenylphosphinopyridin‐(2 H )‐1‐one ligand (see scheme) in the rhodium‐catalyzed hydroformylation of terminal alkenes, as demonstrated by the combination of spectroscopic methods and DFT computations. Hydrogen bonds were also detected in a competent intermediate of the catalytic cycle.