Premium
Intermolecular Gold‐Catalyzed Diastereo‐ and Enantioselective [2+2+3] Cycloadditions of 1,6‐Enynes with Nitrones
Author(s) -
Gawade Sagar Ashok,
Bhunia Sabyasachi,
Liu RaiShung
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201203507
Subject(s) - enantioselective synthesis , scope (computer science) , intermolecular force , scheme (mathematics) , substrate (aquarium) , chemistry , catalysis , computer science , combinatorial chemistry , information retrieval , organic chemistry , mathematics , biology , programming language , molecule , ecology , mathematical analysis
Going for gold : The title reaction has been developed and demonstrates a wide substrate scope with respect to the 1,6‐enynes and nitrones (see scheme; DCE=1,2‐dichloroethane, Tf=trifluoromethanesulfonyl). The results for the enantioselective versions are also presented.