A Mechanically Controlled Indicator Displacement Assay | Zendy

Sakakibara Keita | Zendy; Joyce Leo A. | Zendy; Mori Taizo | Zendy; Fujisawa Takuya | Zendy; Shabbir Shagufta H. | Zendy; Hill Jonathan P. | Zendy; Anslyn Eric V. | Zendy; Ariga Katsuhiko | Zendy

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A Mechanically Controlled Indicator Displacement Assay

Author(s) -

Sakakibara Keita,

Joyce Leo A.,

Mori Taizo,

Fujisawa Takuya,

Shabbir Shagufta H.,

Hill Jonathan P.,

Anslyn Eric V.,

Ariga Katsuhiko

Publication year - 2012

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201203402

Subject(s) - förster resonance energy transfer , displacement (psychology) , monolayer , quenching (fluorescence) , host (biology) , materials science , compression (physics) , fluorescence , nanotechnology , composite material , optics , physics , biology , psychology , ecology , psychotherapist

Push a host : Mechanical compression was applied to a host monolayer at an interface, which facilitated an indicator displacement assay. The fluorescence resonance energy transfer (FRET) between the host and indicator was switched on by this compression. Addition of D ‐glucose caused the indicator to be displaced, effectively quenching the FRET process.

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