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Natural Product Synthesis: Changes over Time
Author(s) -
Hoffmann Reinhard W.
Publication year - 2013
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201203319
Subject(s) - natural (archaeology) , natural product , product (mathematics) , computer science , biochemical engineering , engineering , mathematics , chemistry , history , geometry , archaeology , stereochemistry
For almost 200 years , the synthesis of natural products has been practiced. In this time span, not only the target structures have become increasingly more complex (see two examples from the 1970s), the objectives of natural product synthesis have also changed. Likewise, the standards and criteria for the conduction of natural product synthesis have changed. It is these changes that form the subject of this Essay.