Supramolecular Peptide Amphiphile Vesicles through Host–Guest Complexation

Tricky triggering : Supramolecular peptide amphiphiles were prepared by host–guest complexation of pyrene‐labeled peptides and viologen lipid with cucurbit[8]uril. They self‐assemble into vesicles, which are responsive to a variety of external triggers. Both “switching on” and “switching off” of fluoresence and cytotoxicity is demonstrated in vitro.