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Aptamer‐Based Origami Paper Analytical Device for Electrochemical Detection of Adenosine
Author(s) -
Liu Hong,
Xiang Yu,
Lu Yi,
Crooks Richard M.
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202929
Subject(s) - aptamer , multimeter , fluidics , biosensor , lamination , nanotechnology , materials science , channel (broadcasting) , optoelectronics , electrical engineering , voltage , engineering , biology , genetics , layer (electronics)
Paper biosensors : An origami sensor is printed on a single piece of paper, folded into a three‐dimensional fluidic device, and encapsulated by thermal lamination. Aptamer is trapped in the fluidic channel, where it binds to the target and releases an enzyme to generate a signal. The device is read out using a digital multimeter.