Premium
Straightforward Acid‐Catalyzed Synthesis of Pyrrolyldipyrromethenes
Author(s) -
Yu Changjiang,
Jiao Lijuan,
Tan Xujun,
Wang Jun,
Xu Yajun,
Wu Yangchun,
Yang Gaosheng,
Wang Zhaoyun,
Hao Erhong
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202850
Subject(s) - isoindole , pyrrole , indole test , protonation , catalysis , chemistry , nucleophilic substitution , nucleophile , combinatorial chemistry , medicinal chemistry , organic chemistry , ion
Three for one : Pyrrolyldipyrromethenes having different functional groups were efficiently synthesized from POCl 3 ‐promoted condensations between 5‐chloro‐2‐formylpyrrole or isoindole derivatives and suitable pyrrole or indole fragments through a novel nucleophilic aromatic substitution of the initially formed protonated azafulvene rings.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom