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Design Strategy for DNA Rotaxanes with a Mechanically Reinforced PX100 Axle
Author(s) -
Ackermann Damian,
Jester StefanS.,
Famulok Michael
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202816
Subject(s) - axle , rotaxane , molecular machine , dna , dna origami , dna nanotechnology , materials science , nanotechnology , engineering , chemistry , structural engineering , molecule , supramolecular chemistry , nanostructure , biochemistry , organic chemistry
Non‐deformable axles based on paranemic crossover DNAs can serve as components for mechanically stable DNA rotaxanes. The required design strategies provide generally applicable guidelines for the incorporation of mechanically interlocked DNA architectures or even DNA origami structures. DNA rotaxanes with mechanically reinforced axles can serve as precursors for complex molecular machines capable of force transmission.