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Transition‐Metal‐Free Trifluoromethylaminoxylation of Alkenes
Author(s) -
Li Yi,
Studer Armido
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202623
Subject(s) - transition metal , transition (genetics) , chemistry , organic chemistry , catalysis , biochemistry , gene
No transition metal! Fluorinated hypervalent‐iodine reagents react with TEMPONa in the presence of an alkene under mild conditions to give the corresponding perfluoroalkylaminoxylation products. These radical addition/trapping reactions occur with high stereoselectivity using commercially available reagents, and the product alkoxyamines are readily transformed into the corresponding alcohols.