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Redox Reactions in Palladium Catalysis: On the Accelerating and/or Inhibiting Effects of Copper and Silver Salt Additives in Cross‐Coupling Chemistry Involving Electron‐rich Phosphine Ligands
Author(s) -
Aufiero Marialuisa,
Proutiere Fabien,
Schoenebeck Franziska
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202504
Subject(s) - chemistry , catalysis , phosphine , palladium , copper , catalytic cycle , salt (chemistry) , redox , inorganic chemistry , coupling (piping) , organic chemistry , materials science , metallurgy
Challenging a catalytic cycle : Pd 0 catalysts are readily oxidized by Cu and Ag salts to give dinuclear Pd I complexes and Cu I or Ag I cubanes (see scheme). The reactivities of the resulting Pd I dimers are consistent with several observations of additive effects in cross‐coupling chemistry. The results indicate the possibility for alternative catalytic cycles involving dinuclear Pd I complexes over the currently accepted synergistic cycles involving Pd 0 /Pd II intermediates and Cu or Ag.