Premium
Optimized Use of Reversible Binding for Fast and Selective NMR Localization of Caged Xenon
Author(s) -
Kunth Martin,
Döpfert Jörg,
Witte Christopher,
Rossella Federica,
Schröder Leif
Publication year - 2012
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201202481
Subject(s) - xenon , hyperpolarization (physics) , encoding (memory) , isotopes of xenon , selectivity , chemistry , computer science , nuclear magnetic resonance spectroscopy , artificial intelligence , stereochemistry , biochemistry , organic chemistry , catalysis
The NMR signal of hyperpolarized 129 Xe trapped in cryptophane cages in different solvents experiences different chemical shifts. An encoding method is presented that involves the optimal use of reversible Xe binding and efficiently uses hyperpolarization. This method is utilized in nanomolar imaging, subsecond imaging, and time‐resolved studies while maintaining high spectral selectivity.